Methylation相关论文
目的:探讨O6-甲基鸟嘌呤-DNA甲基转移酶(MGMT)在脑膜瘤组织中的甲基化状态及其对人脑膜瘤细胞系IOMM-Lee细胞生长和转移的作用。方......
目的:应用甲基化芯片与生物信息技术，筛选大气污染细颗粒物（PMn 2.5）对人支气管上皮（HBE）细胞的差异甲基化位点及其包含的基因和通......
The occurrence of osteosarcoma is related to a variety of oncogenes and tumor suppressor genes. DNA methylation is an im......
目的:采用加权基因共表达网络分析（WGCNA）探讨烧伤后瘢痕组织内甲基化基因，发掘瘢痕形成过程中的分子标志物及治疗靶点。方法:采用观......
Nn 6-甲基腺嘌呤(mn 6A)甲基化修饰即RNA腺嘌呤第6位氮原子的甲基化，这一动态过程由编码器、消码器、读码器共同调控。越来......
Highly efficient NHC-iridium-catalyzed β-methylation of alcohols with methanol at low catalyst loadi
The methylation of alcohols is of great importance since a broad number of bioactive and pharmaceutical alcohols contain......
Ovary plays an important role in the female reproductive system.The maintenance and regulation of ovarian function are a......
Catalytic performance of Cu-and Zr-modified beta zeolite catalysts in the methylation of 2-methylnap
2,6-Dimethylnaphthalene (2,6-DMN) is a commercially important chemical for the production of polyethylenenaphthalate and......
Chinese medicine (CM) has contributed to human health care for several thousand years and is still popular in Asian coun......
Objective:To investigate the effects of Zhizi Chuanxiong Capsule (ZCC,栀子川芎胶囊)on abnormal DNA methylation in a rabb......
Obesity-induced sperm DNA methylation changes at satellite repeats are reprogrammed in rat offspring
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Mutual regulation between microRNA-373 and methyl-CpG-binding domain protein 2 in hilar cholangiocar
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Do newly constructed reservoirs always have MeHg pollution problems:A case study from two newly buil
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Release and Methylation from Soil of Mercury Water-Level Fluctuating Zone of the Three Gorges Reserv
In this stage,the concentrations of total mercury increase in water column and decrease in soil.With the prolongation of......
THE METHYLATION STATUS OF THE CPG ISLAND IN THE PROMOTER OF FOXA2 DURING CELLULAR SENESCENCE OF HUMA
Objective: The expression and the methylation level of the CpG island in its promoter of Foxa2 were explored during cell......
Mass spectrometry analysis of the variants of histone H3 and H4 of soybean and their post-translatio
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Simple and rapid method for the determination of dithiocarbamate fungicide residues in vegetables an
A rapid and highly sensitive ultra-high performance liquid chromatography/electrospray ionization mass spectrometry(UPLC......
研究了以环戊二烯、自制催化剂溴化四正丁基铵和一氯甲烷为原料合成甲基环戊二烯的过程.实验结果表明:反应温度及催化剂用量对甲基......
Introduction NLRC5 (NLR family,CARD domain containing 5),known as a new type of NOD-like receptor,can effectively inhibi......
ZBED6 Mediates IGF2 Gene Expression by Regulating Promoter Activity and DNA Methylation in Myoblasts
Zinc finger,BED-type containing 6(ZBED6)is an important transcription factor in placental mammals,affecting development,......
Grafting has been used to improve yield, fruit quality and disease resistance in a range of tree and vegetable species.T......
Xylenes are important feedstock for industrial production of terephthalic acid,isophthalic acid, dimethyl terephthalate,......
Cloning of myosin heavy chain gene from Exopalaemon carinicauda and its expression profiles at diffe
In crustaceans,periodic shedding of the exoskeleton is one of the most important physiological process which is essentia......
Simple and Rapid Method for the Determination of Dithiocarbamate Fungicide Residues in Vegetables an
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Phenotypes that differentiate one individual from another arise by any one or a combination of genetic events (including......
Purpose:Low back pain is a common intervertebral disc degenerative disease.Apoptosis of nucleus pulposus cells plays an ......
Identification of aberrantly methylated differentially expressed genes in HCC using integrated bioin
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DOK6 promoter methylation serves as an independent prognostic biomarker in de novo acute myeloid leu
Objective AML is a heterogeneous group of clonal hematopoietic stem-cell disorders that is now cured in 35 to 40%of adul......
Promoter methylation of the candidate tumor suppressor gene TCF21 in myelodysplastic syndrome and ac
Objective Transcription factor 21(TCF21)has been identified as a candidate tumor suppressor gene epigenetically inactiva......
Upregulation of FRα by Decitabine Sensitizes Acquired Radioresistant Lung Adenocarcinoma Cells to Pe
Objective The radiation resistance of lung adenocarcinoma remains a major therapeutic problem,and chemotherapy drugs are......
Demethylation-mediated upregulation of melanomaassociated antigen-A11 correlates with malignant prog
Objective Esophageal carcinoma is a malignant tumor that threatens human life and health,the incidence and mortality of ......
Analysis of differentially methylated expressed genes and pathways in lung adenocarcinoma based on b
目的 The aim of this study was to identify methylated-differentially expressed genes in LUAD and explore pathways throug......
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目的 在世界范围内，原发性肝癌是导致患者死亡的第二大肿瘤，约90％的原发性肝癌是肝细胞癌(HCC)。肿瘤干细胞被认为是肿瘤发生和转移的......
目的 MoreevidencesuggestthathOGG1playsaroleinseveraldiseasepathways,includingvariouscancers.Nevertheless,howhOGG1isregul......
A novel PADI4/SOX4/PU.1 signaling pathway is involved in the committed differentiation of acute prom
Aims: The hematologic malignancy acute promyelocytic leukemia (APL) exhibits a failure of myeloid differentiation.Most p......
Background: Mild cognitive impairment(MCI)is an intermediate period between normal ageing and Alzheimer disease....
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Ubiquitin E3 ligase SPOP regulates the stability of histone H3K36 methyltransferase SETD2 and DNA da
Trimethylation of histone H3K36 is a chromatin mark associated with active gene expression, which has been implicated in......
An epigenetic biomarker combination of eomes, pcdh17, and pou4f2 detects bladder cancer accurately f
Background: To recognize a novel and optimized combination of epigenetic biomarkers capable of returning higher sensitiv......
Berberine has been extensively used to treat intestinal infections,particularly bacterial diarrhea for thousands of year......
The emergence of multiple drug resistant microorganisms has caused major health concern worldwide....
Lysine Monomethylation is Critical for IRF4-Mediated Transcriptional Regulation of Th2 Lineage Commi
Interferon regulatory factor 4 (IRF4) regulates the transcription of genes essential for the differentiation and functio......
Integrated analysis of microRNA and mRNA expression reveals insights into unstability of secondary m
Plant cell culture technology is a promising alternative for production of high-value secondary metabolites,but limited ......
